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Aspedon Co-Authors Article for Journal of Bacteriology

May 10, 2006

An article co-authored by Southwestern Oklahoma State University Associate Professor Dr. Arden Aspedon was published in the April 2006 edition of the Journal of Bacteriology.

“Microarray Analysis of the Osmotic Stress Response in Pseudomonas aeruginosa” was authored by Aspedon and Kelli Palmer and Marvin Whiteley, both from the University of Oklahoma Health Sciences Center.

In their studies, transcriptional profiling of Pseudomonas aeruginosa grown under steady-state hyperosmotic stress conditions showed an up-regulation of genes associated with osmoprotectant synthesis, putative hydrophilins, and the type III secretion system with associated cytotoxins.

A large number of regulatory genes, including several two-component systems not previously known to be influenced by osmolarity, were differentially expressed by P. aeruginosa in immediate response to hyperosmotic shock.

Aspedon is director of the MicroBiological Sciences-Medical Technology program at SWOSU.

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